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DOI:10.14740/jmc4191 - Corpus ID: 269245795
@article{Mammarella2024RefractoryPO, title={Refractory Pseudomonas Osteomyelitis of the Skull Base With Gradenigo’s Syndrome: Early Dysphagia and Late Abducens Nerve Palsy}, author={Fulvio Mammarella and Antonella Loperfido and Gianluca Velletrani and Francesco Casorati and Alessandro Stasolla and Stefano Di Girolamo and Gianluca Bellocchi}, journal={Journal of Medical Cases}, year={2024}, volume={15}, pages={43 - 48}, url={https://api.semanticscholar.org/CorpusID:269245795}}
- F. Mammarella, A. Loperfido, G. Bellocchi
- Published in Journal of Medical Cases 1 April 2024
- Medicine
A 71-year-old man with a previous history of otitis media and poorly controlled type 2 diabetes mellitus with facial pain, left hemilarynx paralysis, dysphagia and otorrhea is presented, the only case with a delayed onset of abducens nerve palsy.
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38 References
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Medicine
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A Gradenigo's syndrome caused by chronic inflammation with good response to steroids is reported, a 35-year-old female who presented with right temporal headache and right retro-orbital pain and the MRI performed after three months recorded no brain inflammation.
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While a variety of different surgical approaches can be used in treatment of PA, the MCF approach is recommended in cases where access to the anterior petrous apex may be challenging via transcanal or transmastoid approach.
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A patient presenting with symptoms reflective of a sinus infection unrelieved by antibiotics with concomitant cranial nerve deficits should raise clinical concern for an intracranial pathology rather than a simple case of sinusitis.
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Medicine
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The case of an 81-year-old man with a previous history of recurrent otitis media, who presented withGradenigo’s syndrome and septic lateral sinus thrombosis is presented.
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BMC Infectious Diseases
Drug treatment is conservative but efficient method in this case of fungal petrositis, and mNGS can provide pathogenic reference, when antibiotic is not efficient enough for fungal infections or drug-resistantfungal infections cases.
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A 67-year-old man who presented with an incomplete triad of symptoms of GS that failed medical therapy and was successfully treated with surgical intervention (mastoidectomy and petrous apicectomy) is presented.
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This study describes a case of primary IgG4-RD of the petrous apex of the temporal bone that presented with diplopia and was diagnosed by middle fossa craniotomy and temporal bone biopsy, thought to be the first case description where primary diagnosis was made based on middle cranial fosso craniotom and temporalBone biopsy.
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The classic clinical constellation of this entity, referred to as Gradenigo’s triad, consists of an ipsilateral abducens nerve palsy, severe pain in the trigeminal nerve distribution, and bacterial otitis media.
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